Federal small business grants
Page 3 of 31 • Last updated May 5, 2026
451 federal funding opportunities are currently open to small businesses, sourced directly from Grants.gov listings across federal agencies. These are direct-from-federal programs (separate from state-administered funding) — each listing links to the official application so you can confirm eligibility and submit directly.
- Operation and Management of the Edward M. Kennedy CenterMay 5, 2026
U.S. Embassy Dhaka seeks a nonprofit organization to manage and operate the Edward M. Kennedy Center, advancing U.S. foreign policy through programs in education, commerce, and cultural exchange for Bangladeshi professionals and exchange alumni.
- DoW, Ovarian Cancer, Ovarian Cancer Academy – Early-Career Investigator AwardMay 5, 2026
Department of Defense Ovarian Cancer Academy Early-Career Investigator Award provides mentoring, networking, and collaborative research training for junior faculty conducting ovarian cancer research through a virtual platform.
- DoW Pancreatic Cancer Research Program, Focused Pilot AwardMay 5, 2026
Department of Defense Pancreatic Cancer Research Program Focused Pilot Award supports patient-centered pancreatic cancer research concepts with preliminary data for FY26; clinical trials are not eligible.
- CCRP Initiative: Promoting a Basic Understanding of Chemical Threats to Skin (R01 Clinical Trial Not Allowed)May 5, 2026
NIH Chemical Countermeasures Research Program funds basic research into pathological mechanisms of skin injuries from government-identified toxic chemicals; clinical trials not eligible.
- Research Opportunities in Cancer Epidemiology Cohort Studies (U01 Clinical Trial Not Allowed)May 5, 2026
National Cancer Institute funds cancer epidemiology cohort studies addressing knowledge gaps in etiology and survivorship through hypothesis-based research, infrastructure support, and data-sharing initiatives.
- Coccidioidomycosis Collaborative Research Centers (P01 Clinical Trial Not Allowed)May 5, 2026
NIAID solicits applications for Coccidioidomycosis Collaborative Research Centers to fund multi-disciplinary teams conducting translational and clinical research toward developing a Valley fever vaccine.
- NEA Grants for Arts Projects 2, FY 2027May 5, 2026
National Endowment for the Arts Grants for Arts Projects provides funding to 501(c)(3) nonprofits, government units, and tribal organizations for arts projects across multiple disciplines; requires 1:1 cost share match.
- DoW Pancreatic Cancer Research Program, Idea Development AwardMay 5, 2026
Department of Defense Pancreatic Cancer Research Program Idea Development Award funds innovative high-risk/high-reward research projects addressing FY26 focus areas, with up to higher funding available for early-career investigator partnerships with…
- DoW Amyotrophic Lateral Sclerosis Research Program, Pilot Clinical Trial AwardMay 5, 2026
Department of War's FY2026 Amyotrophic Lateral Sclerosis Research Program provides pilot clinical trial funding for phase 1 to small-scale phase 2 ALS studies focusing on biomarker-driven interventions or clinical care, with trials required to begin…
- Tuberculosis Research Advancement Centers (TRACs) (P30 Clinical Trial Not Allowed)May 5, 2026
NIH Tuberculosis Research Advancement Centers program funds multidisciplinary TB research centers to develop researchers and advance basic and clinical science, excluding clinical trials.
- Manufacturing in America E2G Grant InitiativeMay 5, 2026
SBA Manufacturing in America E2G Grant Initiative provides funding to organizations offering hands-on manufacturing training and technical assistance to eligible small manufacturing businesses.
- NIJ FY25 Research and Evaluation on Drugs and Crime: Nexus with Firearms and ViolenceMay 5, 2026
NIJ FY25 program funds research on drug crimes and firearms intersection to develop evidence-based tools and practices for law enforcement and criminal justice agencies across four topic areas: pattern identification, interdiction strategies, prosec…
- DoW Amyotrophic Lateral Sclerosis Research Program, Therapeutic Idea AwardMay 5, 2026
Department of Defense Amyotrophic Lateral Sclerosis Research Program Therapeutic Idea Award supports high-risk, innovative ALS drug and therapy discovery projects with fiscal year 2026 funding.
- DoW Amyotrophic Lateral Sclerosis Research Program, Therapeutic Development AwardMay 5, 2026
Department of War Amyotrophic Lateral Sclerosis Research Program Therapeutic Development Award funds preclinical-to-IND therapeutic research with proof-of-concept efficacy data and mechanism-specific biomarker development for fiscal year 2026.
- Grant Administration for Binational Centers (BNCs) in ArgentinaMay 5, 2026
U.S. Embassy Buenos Aires seeks a Grant Administrator to distribute $57,000 USD among twelve Binational Centers across Argentina for English language instruction and cultural programming.